
Nervigesic 450mg — Pregabalin Capsules
Pregabalin
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KAM4U10Pregagesic 300: pregabalin 300 mg capsules, the largest Lyrica capsule strength; dosed by a doctor within 150–600 mg a day.
| Active ingredient & strength | Pregabalin 300 mg |
|---|---|
| Format | Capsule |
| Legal status | Prescription-only medicine in the EU/EEA |
| EU reference medicine | Lyrica — EMA product information (EPAR) |
| Price | From €40.00 (1 Strip/15 pills) · from €2.53 per pill (10 Strip/ 150 pills) |
| Delivery | 3–5 working days to most EU/EEA countries (2–7 by country) |
| Availability | In stock |
Generic Pregabalin — Pregagesic 300 — Pregabalin Capsules. Available in multiple pack sizes.
Price range
Dispatched within one working day of payment
Pack size & pricing
3 · click to add
€2.67 per unit
€40.00
€2.60 per unit
€195.00
€2.53 per unit
€380.00
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Sealed manufacturer packs
Sealed manufacturer blisters or sachets with the batch number and expiry date printed, and the patient information leaflet in every box.
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Tracked shipping on every parcel. If a parcel is lost, we investigate with the courier and resolve it with a replacement shipment or another appropriate solution (see our delivery policy).
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What happens after you order
Order & pay — order and payment confirmed by email
We pack — sealed packs, plain outer box
Dispatched within 1 working day of payment — tracking number emailed
Delivered — 3–5 working days to most EU/EEA countries (2–7 by country), nothing on the outside
Pregagesic 300: pregabalin 300 mg capsules, the largest Lyrica capsule strength; dosed by a doctor within 150–600 mg a day.
Part of our Pregabalin range.
Pregagesic 300 contains 300 mg of pregabalin per capsule. In the EU, pregabalin (as Lyrica) is authorised for neuropathic pain, as add-on treatment for partial seizures and for generalised anxiety disorder, and it is a prescription-only medicine in the EU/EEA. The Lyrica product information sets a daily total of 150 to 600 mg, split into two or three doses and adjusted by the prescriber in stages, so whether 300 mg capsules fit your regimen is your doctor's decision. Pregagesic has no EU marketing authorisation, so no EU authority has assessed it against Lyrica. It is not a casual painkiller: pregabalin works on nerve signalling, not inflammation, and needs medical oversight.
Pregabalin is absorbed quickly, with blood levels peaking roughly an hour after a dose, but the therapeutic effect on nerve pain is not instant. Per the patient leaflet, some people notice improvement within the first week of regular use, while the full effect typically builds over one to two weeks of consistent dosing. Pregabalin is taken as an ongoing course at the schedule your prescriber sets — not as a one-off tablet when pain flares. Because the effect depends on steady levels, missing doses or stopping abruptly undermines results and can trigger withdrawal symptoms. Always taper under medical guidance rather than stopping Pregagesic 300 suddenly.
The pregabalin capsules we stock run from 150 mg to 450 mg. The Lyrica product information sets a daily total of 150 to 600 mg, split into two or three doses and adjusted by the prescriber in stages. Nervigesic 150mg contains half as much as Pregagesic 300, and Nervigesic 450mg more than any single Lyrica capsule, so it is only for a doctor's explicit instruction; side effects such as dizziness and drowsiness rise with dose.
Read the patient leaflet before your first capsule and follow your prescriber's schedule exactly; the Lyrica product information says pregabalin can be taken with or without food. Never drink alcohol with Pregagesic 300: the combination amplifies drowsiness, dizziness, and breathing suppression. Do not drive or operate machinery until you know how it affects you. Pregabalin carries a recognised risk of dependence, so use only the dose agreed with your doctor, never share capsules, and never increase the dose yourself. If you plan to stop, ask your doctor for a tapering plan — abrupt discontinuation can cause insomnia, headache, nausea, and anxiety.
Every Pregagesic 300 pack we dispatch is sealed manufacturer stock with the batch number and expiry date printed on the blister and carton, plus the patient information leaflet inside. Orders are dispatched within one working day of payment in plain, unbranded packaging, with tracking on every parcel; standard delivery takes 3–5 working days to most EU and EEA countries (2–7 by country) and is free over €110. If anything about your pack looks wrong on arrival, contact us before taking it.
Like all pregabalin products, Pregagesic 300 can cause side effects, and at 300mg per capsule they can be noticeable. The most common are dizziness, drowsiness, blurred vision, dry mouth, weight gain, and swelling of the hands or feet. Some people also report difficulty concentrating or mild coordination problems, especially in the first week. These effects generally scale with dose, so a 300mg capsule is more likely to cause them than a 75mg or 150mg one. Rare but serious reactions include severe allergic swelling of the face or throat (angioedema), difficulty breathing, mood changes or thoughts of self-harm, and severe skin rash — stop the medicine and seek medical help immediately if any of these occur. Never combine it with alcohol or other sedatives.
Pregagesic 300 has dependence potential, so it is not suitable for everyone. Do not take it if you are allergic to pregabalin or any capsule ingredient. It should be avoided, or used only under close medical supervision, by anyone with a history of drug or alcohol dependence, breathing problems such as COPD or sleep apnoea, or significant kidney disease — pregabalin is cleared by the kidneys and doses must be reduced. Combining it with alcohol, opioids, benzodiazepines, or sleeping tablets like zopiclone dangerously increases sedation and breathing suppression. Elderly people are more prone to dizziness and falls and usually need lower doses. It is not recommended in pregnancy or breastfeeding without a doctor's explicit advice.
Store Pregagesic 300 in a cool, dry place below 25–30°C, away from direct sunlight and moisture — a bedroom drawer is better than a bathroom cabinet. Keep the capsules in their original sealed blister until the moment you take one, and always out of reach of children and pets. To verify authenticity, check that each blister pocket is intact and unbroken, that the foil is printed with a batch number and a clear expiry date, that the outer box is undamaged and matches the blister details, and that a patient information leaflet is included. If anything looks tampered with, do not take the capsules.
Current prices: 1 Strip / 15 pills for €40.00 (€2.67 per pill), 5 Strip / 75 pills for €195.00 (€2.60 per pill) and 10 Strip / 150 pills for €380.00 (€2.53 per pill). Buying 10 Strip / 150 pills works out 5% cheaper per pill than the smallest pack. Buy only the quantity your prescription covers before the printed expiry date.
General information about the active ingredient in Pregagesic 300 — Pregabalin Capsules.
See the full Pregabalin guide & all Pregabalin productsPregabalin is a prescription-only medicine in the EU/EEA and the active substance of Lyrica. Its EU product information authorises it in adults for peripheral and central neuropathic (nerve) pain, as add-on treatment for partial seizures, and for generalised anxiety disorder. It can cause dependence, even at therapeutic doses, so it should be used only under medical supervision.
Pregabalin is a gamma-aminobutyric acid (GABA) analogue, but it does not act directly on GABA receptors. It binds to an auxiliary subunit (the alpha-2-delta protein) of voltage-gated calcium channels in the central nervous system, which reduces the release of several excitatory neurotransmitters involved in pain signalling, seizure activity and anxiety. It is absorbed quickly, with peak blood levels within about an hour, and is removed from the body mainly unchanged through the kidneys.
Take pregabalin exactly as prescribed. The EU product information describes a daily dose range of 150 to 600 mg, given in two or three divided doses, usually started low and increased step by step over one to a few weeks depending on response and side effects; your doctor sets and adjusts your dose. It can be taken with or without food. People with reduced kidney function need a lower dose. Never stop suddenly: the EU product information recommends stopping gradually over at least one week.
Common (usually mild and temporary):
Stop and seek medical help if you experience:
Store in the original packaging out of the sight and reach of children, and do not use after the expiry date. The EU product information states no special storage conditions are required. Return unused medicine to a pharmacy for safe disposal.
Its EU product information authorises it in adults for peripheral and central neuropathic (nerve) pain, as add-on treatment for partial seizures with or without secondary generalisation, and for generalised anxiety disorder.
No. Withdrawal symptoms reported after stopping include insomnia, headache, nausea, anxiety, diarrhoea, flu-like symptoms, nervousness, depression, pain, sweating, dizziness and seizures. The EU product information recommends stopping gradually over at least one week.
Yes. The EU product information states that pregabalin can cause drug dependence, which may occur at therapeutic doses, and that cases of misuse and abuse have been reported. Take it only as prescribed and never share it.
Pregabalin can add to the effects of alcohol and other sedatives. With opioids there have been reports of respiratory failure, coma and deaths, and a study linked the combination to a higher risk of opioid-related death. Discuss any such use with your doctor.
The EU product information warns that use in the first trimester may cause major birth defects and that pregabalin should not be used in pregnancy unless clearly necessary. Women who could become pregnant must use effective contraception during treatment.
Gabapentin also acts on the nervous system and is authorised for peripheral neuropathic pain and epilepsy. Duloxetine is an antidepressant authorised for diabetic peripheral neuropathic pain, depression and anxiety. Pregabalin is the only one of the three authorised for central neuropathic pain. See the comparison table on this page.
Important: This information is general and not a substitute for medical advice. Always read the patient information leaflet supplied with your medicine and consult a doctor or pharmacist before use — especially if you have existing health conditions or take other medication.
The larger the pack, the lower the price per unit.
Pregagesic 300 — Pregabalin Capsules isn't stocked on European high-street pharmacy shelves — it's an imported generic, so buying happens online. Kam4eu ships sealed Pregagesic 300 — Pregabalin Capsules from €40.00 (3 pack sizes, lower per-unit price on larger packs) to all 27 EU + 3 EEA countries. Orders dispatch within one working day of payment; standard delivery takes 3–5 working days to most EU/EEA countries (2–7 by country), free over €110.00.
Pregagesic 300 — Pregabalin Capsules starts from €40.00. Several pack sizes are available — the larger the pack, the lower the per-unit price. European delivery is free on orders over €110, otherwise €20 standard (3–5 working days to most countries, 2–7 by country).
Orders ship in plain, unbranded packaging from our European fulfilment hub, usually within one working day of payment clearing. Standard delivery reaches all 27 EU + 3 EEA countries in 3–5 working days to most of them (2–7 depending on the country); express (1–2 working days) is also available. For EU orders, VAT and duties are settled at checkout via IOSS, so there are no surprise bills on arrival.
The active ingredient in Pregagesic 300 — Pregabalin Capsules is Pregabalin. Always read the patient information leaflet and consult a doctor or pharmacist before first use.
Choose your method at checkout: secure bank/SEPA transfer or PayPal. You'll receive clear payment confirmation by email, and we dispatch within one working day of payment clearing.
Yes. Every order ships in plain, unbranded outer packaging — nothing on the outside indicates the contents or the pharmacy.
Both contain 300 mg of pregabalin. Lyrica is the EU-authorised reference medicine; Pregagesic has no EU marketing authorisation, so no EU authority has assessed it against Lyrica. Inactive ingredients and capsule appearance may differ. If you are switching brands, mention it to your doctor or pharmacist.
That is a decision for your doctor. The Lyrica product information sets a daily total of 150 to 600 mg, split into two or three doses and adjusted by the prescriber in stages, based on response and tolerability; higher doses raise the risk of dizziness, drowsiness and other side effects. Speak to your doctor before any pregabalin treatment.
Pregabalin carries a recognised risk of dependence, particularly at higher doses or with a history of substance misuse, and it is a controlled substance in several countries. Take only the dose your doctor prescribes, never increase it yourself, and always taper off gradually under medical guidance rather than stopping abruptly.
Current prices: 1 Strip / 15 pills for €40.00 (€2.67 per pill), 5 Strip / 75 pills for €195.00 (€2.60 per pill) and 10 Strip / 150 pills for €380.00 (€2.53 per pill). Buying 10 Strip / 150 pills works out 5% cheaper per pill than the smallest pack. Delivery across the EU and EEA takes 3–5 working days and is free on orders over €110 — roughly two packs.
No. Alcohol and pregabalin both depress the central nervous system, and together they multiply drowsiness, dizziness, and the risk of dangerously slowed breathing. Avoid alcohol entirely while taking Pregagesic 300, particularly at this 300mg strength. If you drink regularly, tell your doctor before starting the medicine.
The Lyrica product information says pregabalin can be taken with or without food. Take it at the times your prescriber set, exactly as directed.
No. These are hard capsules, not scored tablets, and opening them gives an unreliable dose. If 300mg is too strong for you, the correct approach is a lower-strength pregabalin product prescribed by your doctor — 75mg and 150mg capsules exist for exactly this reason.
Pregabalin has a half-life of around 6 hours in people with normal kidney function, so most of a dose is cleared within about 1–2 days. It clears more slowly if your kidneys are impaired. Effects on alertness can persist, so avoid driving until you know how it affects you.
Do not stop abruptly. Sudden discontinuation can cause withdrawal symptoms such as insomnia, headache, nausea, anxiety, and sweating — a known feature of pregabalin as a dependence-forming medicine. Doses should be tapered down gradually over at least a week, under your doctor's guidance.
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Reviewed by the Kam4eu editorial teamMedicine information reviewed 13 August 2026Next review due 13 August 2027
Sources for the medical information on this page
This page is general product and medicine information, not a prescription or a substitute for medical advice. Always read the patient information leaflet supplied with your medicine, and speak to a doctor or pharmacist before starting Pregagesic 300 — especially if you take other medicines or have a heart, liver or kidney condition.