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Active ingredient

Zopiclone

Zopiclone is a prescription medicine used for the short-term treatment of insomnia (difficulty falling asleep, waking during the night, or early-morning waking). It belongs to a group of medicines often called 'Z-drugs' (non-benzodiazepine hypnotics), which act in a similar way to benzodiazepines. Because of the risk of tolerance and dependence, it is normally prescribed only for a short period and is a controlled drug in many European countries.

Reviewed by the Kam4eu Pharmacy Team on 21 June 2026 · Next review June 2027

Zopiclone medicines we deliver

Browse the full Sleep Aids & Wakefulness range

2 generic Zopiclone products — same molecule, different brands, formats and pack sizes.

How it works

Zopiclone works on the brain and central nervous system to promote sleep. It enhances the effect of a natural calming chemical called GABA (gamma-aminobutyric acid), which reduces the activity of nerve cells. This produces a sedative effect that can help you fall asleep more quickly, reduce night-time waking and improve overall sleep quality for a short time.

How it is taken

Always take zopiclone exactly as prescribed and as described in the patient information leaflet. It is taken by mouth, usually just before going to bed, and only when you are able to get a full night's sleep. Do not take more than the prescribed amount, do not take it for longer than recommended (usually no more than 2-4 weeks including any tapering), and do not take a second dose during the same night.

Side effects

Common (usually mild and temporary):

  • A bitter or metallic taste in the mouth
  • Daytime drowsiness, tiredness or feeling 'hungover' the next day
  • Dry mouth
  • Headache
  • Dizziness or light-headedness

Stop and seek medical help if you experience:

  • Memory problems (amnesia), or carrying out activities such as walking, eating or driving while not fully awake with no memory of it afterwards
  • Changes in mood or behaviour, such as agitation, aggression, confusion, hallucinations or worsening depression
  • Signs of an allergic reaction, such as swelling of the face, lips or throat, or difficulty breathing
  • Dependence (addiction) and withdrawal symptoms when stopping, especially after prolonged use
  • Falls, particularly in older people

Safety & who should not take it

  • Do not drink alcohol while taking zopiclone; combining the two greatly increases drowsiness and the risk of serious breathing problems.
  • Do not drive or operate machinery until you know how zopiclone affects you, as next-day impairment is common; it is an offence to drive while impaired.
  • Tell your doctor about all other medicines, especially other sedatives, strong painkillers (opioids), muscle relaxants or medicines for anxiety.
  • Use is intended for short-term treatment only; long-term use can lead to tolerance, dependence and difficult withdrawal.
  • Tell your doctor before use if you have breathing problems, liver or kidney disease, myasthenia gravis, sleep apnoea, or a history of alcohol or drug misuse or depression.
  • Not recommended during pregnancy or breastfeeding, or for children.
  • Older adults may be more sensitive and are at greater risk of drowsiness, confusion and falls.

Storage

Store in the original packaging below 25°C, away from direct heat, light and moisture, and out of the sight and reach of children. As a controlled medicine, return any unused tablets to a pharmacy for safe disposal.

Frequently asked questions

Is zopiclone addictive?+

It can be. Tolerance and dependence can develop, especially with regular use beyond a few weeks. To reduce this risk it is prescribed for short periods only, and your doctor may lower the dose gradually rather than stopping suddenly.

Can I drive the morning after taking zopiclone?+

Not necessarily. Zopiclone can cause drowsiness and slowed reactions that last into the next day. Do not drive if you feel in any way impaired, and allow enough time for a full night's sleep first.

Can I drink alcohol while taking zopiclone?+

No. Alcohol adds to the sedative effect and can cause excessive drowsiness and dangerous breathing problems. You should avoid alcohol completely while taking this medicine.

Important: This information is general and not a substitute for medical advice. Always read the patient information leaflet supplied with your medicine and consult a doctor or pharmacist before use — especially if you have existing health conditions or take other medication.

Zopiclone health guides

Zopiclone for Insomnia: A Short-Term Guide

How Zopiclone is used to manage short-term insomnia, why it should only be taken briefly, and the key safety points to discuss with your doctor.

Read guide

Zopiclone for Insomnia: A Short-Term Sleep Aid Explained

How zopiclone works for short-term insomnia, why courses are kept brief, and the dependence risks to discuss with your doctor.

Read guide

Zopiclone vs Other Sleep Aids: Understanding Short-Term Insomnia Options

How zopiclone compares with other short-term sleep aids, including its benefits, risks and the importance of dependence awareness.

Read guide