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Condition guide

Erectile Dysfunction

Erectile dysfunction (ED) is the persistent difficulty in getting or keeping an erection firm enough for satisfying sex. It is very common, especially as men get older, and it is usually treatable. Occasional difficulty is normal, but ongoing problems are worth discussing with a doctor or pharmacist.

Reviewed by the Kam4eu Pharmacy Team on 13 August 2026 · Next review August 2027

Recognising the signs

  • Trouble getting an erection on most occasions when you want one
  • Difficulty keeping an erection long enough for sex
  • Erections that are softer or less reliable than they used to be
  • Reduced sexual desire alongside erection difficulties
  • Increasing worry or anxiety about sexual performance

Common causes

  • Reduced blood flow linked to high blood pressure, high cholesterol or narrowed arteries
  • Diabetes, which can affect both blood vessels and nerves
  • Hormonal factors such as low testosterone
  • Psychological factors including stress, anxiety, depression and relationship difficulties
  • Some prescription medicines, including certain antidepressants and blood pressure treatments
  • Smoking, excessive alcohol and being significantly overweight
  • Nerve damage from surgery, injury or conditions such as multiple sclerosis

Treatment options we stock

The most common treatments are PDE5 inhibitor tablets such as sildenafil, tadalafil, vardenafil and avanafil, which improve blood flow to the penis to help you get and keep an erection when sexually aroused. They differ in how quickly they work and how long the effect lasts, so a doctor or pharmacist can help you choose. Always read the patient information leaflet, and never take a PDE5 inhibitor with nitrate medicines (used for chest pain or heart conditions), as the combination can cause a dangerous drop in blood pressure.

Sildenafil Tadalafil Vardenafil Avanafil
Browse the full Erectile Dysfunction range

Lifestyle & self-care support

  • Stop smoking and keep alcohol within recommended limits
  • Stay physically active and aim for a healthy weight
  • Eat a balanced diet that supports heart and circulation health
  • Manage stress and address anxiety, low mood or relationship issues
  • Have blood pressure, cholesterol and blood sugar checked regularly
  • Talk openly with your partner to reduce performance pressure

How to choose & when to see a doctor

Because ED can be an early warning sign of heart or circulation problems, it is sensible to see a doctor for an assessment rather than treating it in isolation. A clinician can review your general health and current medicines and recommend the most suitable option. Seek prompt medical advice if ED comes on suddenly, alongside chest pain, or if an erection lasts more than a few hours.

Frequently asked questions

Is occasional erectile difficulty something to worry about?+

Most men experience an off night now and then, often due to tiredness, stress or alcohol, and this is not usually a cause for concern. ED becomes worth investigating when the difficulty happens regularly over several weeks or months. Persistent problems can sometimes point to an underlying health issue, so it is worth raising with a doctor.

Do ED tablets work straight away?+

PDE5 inhibitors do not cause an automatic erection; you still need to be sexually aroused for them to work. How quickly they take effect and how long they last varies between medicines, which is one reason to read the leaflet and follow professional advice. They do not increase desire on their own.

Can I take an ED treatment if I have heart problems?+

PDE5 inhibitors must never be combined with nitrate medicines used for angina or certain heart conditions, as this can cause a serious drop in blood pressure. If you have any heart or circulation condition, tell your doctor before starting treatment. They can confirm whether it is safe for you.

Will lifestyle changes really make a difference?+

Yes. Stopping smoking, drinking less, staying active and managing stress can all improve erectile function, sometimes significantly. Because good blood flow is central to erections, anything that benefits your heart and circulation tends to help.

Should I see a doctor or just try a treatment?+

A medical assessment is recommended because ED can be an early sign of conditions such as cardiovascular disease or diabetes. A doctor can check your overall health, review your medicines and choose a treatment that suits you. Always read the patient information leaflet before starting anything.

Erectile Dysfunction health guides

Tadalafil for Men: The 'Weekend' ED Option Explained

Summary: Tadalafil, the active ingredient behind the branded tablet Cialis, is a PDE5 inhibitor that can remain effective for up to 36 hours — considerably longer than shorter-acting alternatives like sildenafil — giving some men more flexibility around timing. This guide explains how it works, how it differs from sildenafil, the nitrate interaction that must always be avoided, and why suitability should be confirmed by a clinician rather than chosen independently.

Read guide

Cialis for Men: What Tadalafil Does and Who It Suits

Summary: Tadalafil is the active ingredient behind Cialis, a PDE5 inhibitor valued for its comparatively long duration of action, which allows either on-demand or daily dosing patterns depending on lifestyle and medical advice. This guide explains how it works, who tends to find it suitable, and the safety considerations — including the nitrate interaction — that make professional guidance essential. Kam4eu supplies generic tadalafil, chemically identical to the branded product, across the UK and EU/EEA.

Read guide

Generic Sildenafil: The Complete Buyer's Guide

Summary: Generic sildenafil contains the same active ingredient as the original branded medicine and, when sourced from GMP-certified manufacturers, offers comparable quality at a lower cost. This guide explains how sildenafil works, what strengths and formats are available, the key safety point about never combining PDE5 inhibitors with nitrates, and how to verify a genuine product through batch numbers, manufacturer transparency, and proper packaging — while leaving the actual dose decision to your doctor or pharmacist.

Read guide

Is There a 'Better' Viagra? Comparing Your Options

Summary: There's no single "better" PDE5 inhibitor — sildenafil, tadalafil, vardenafil and avanafil all work the same way but differ in onset, duration and sensitivity to food, so the right choice depends on your routine and how your body responds. Sildenafil and vardenafil act faster with a shorter window and are more affected by meals, while tadalafil lasts far longer and avanafil can act quickly with a moderate duration. Whichever you're considering, PDE5 inhibitors must never be combined with nitrates, and the final decision should always involve the patient leaflet and a doctor or pharmacist.

Read guide

Important: This information is general and not a substitute for medical advice. Always read the patient information leaflet supplied with your medicine and consult a doctor or pharmacist before starting treatment.

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