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Zopisign 10mg — Zopiclone Tablets
Zopiclone
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Sleep Aids & Wakefulness
Generic zopiclone for short-term insomnia, and modafinil for excessive daytime sleepiness caused by narcolepsy.
4 productsZopicloneModafinil Free over €110
Two distinct families: Zopiclone for short-term insomnia, and Modafinil for excessive daytime sleepiness caused by narcolepsy — its only EU use since the European Medicines Agency's 2010 review.
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Zopisign 7.5mg — Zopiclone Tablets
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Modafinil 200mg Tablets
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Modafinil 100mg Tablets
Modafinil
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About Sleep Aids & Wakefulness
This category contains two very different types of medicine. Zopiclone is a short-term sleeping tablet (a 'Z-drug') used to help with insomnia — falling asleep, staying asleep, or early waking. Modafinil is the opposite: a wakefulness-promoting medicine which, in the EU, is used only for excessive daytime sleepiness caused by narcolepsy. The European Medicines Agency removed its former uses for shift-work sleep disorder, obstructive sleep apnoea and idiopathic hypersomnia after a 2010 review.
Both are prescription-only medicines in the EU/EEA, intended for specific medical situations. Zopiclone is used only for short periods — at most four weeks including tapering off — because of the risk of tolerance and dependence; Modafinil promotes wakefulness but does not replace genuine sleep. Each product page explains its specific use and precautions.
What it's used for
- Short-term insomnia that is severe, disabling or very distressing — Zopiclone
- Excessive daytime sleepiness caused by narcolepsy — Modafinil (its only EU indication)
How to choose
Choose based on the problem: Zopiclone is for difficulty sleeping at night and is used only short-term; Modafinil is for staying awake during the day in narcolepsy. They are not interchangeable. Within each, the strengths differ — your doctor will advise what's appropriate. Never use a wakefulness agent to mask a lack of sleep, or a sleeping tablet long-term.
Safety essentials
- Zopiclone is for short-term use only (at most 4 weeks including tapering off) — longer use risks tolerance and dependence.
- Do not drink alcohol with Zopiclone, and don't drive while affected — next-day impairment is common.
- Modafinil can reduce the effectiveness of hormonal contraception — use an additional method during treatment and for up to two months after.
- Zopiclone can cause dependence, and modafinil's EU product information says dependence with long-term use cannot be excluded — take both exactly as prescribed and never share them.
- Always read the patient information leaflet and consult a doctor or pharmacist.
Frequently asked questions
Is Zopiclone addictive?+
It can be — tolerance and dependence can develop, so it's prescribed for short periods only and the dose may be reduced gradually rather than stopped suddenly.
Does Modafinil replace sleep?+
No. It reduces excessive sleepiness and promotes wakefulness but doesn't remove the body's need for sleep or treat the underlying cause of tiredness.
Can I take a sleeping tablet and a wakefulness tablet?+
These are for different problems and should only be used as a doctor directs. Don't combine or self-medicate; speak to a healthcare professional about your sleep pattern.
Is modafinil used for shift work in the EU?+
No longer. After a 2010 review, the European Medicines Agency restricted modafinil to excessive sleepiness caused by narcolepsy; it should no longer be used for shift-work sleep disorder, obstructive sleep apnoea or idiopathic hypersomnia, because the evidence of benefit did not outweigh the risks.
Important: This is general information, not medical advice. Always read the patient information leaflet and consult a doctor or pharmacist before use.
Sources
- Chronic Insomnia — StatPearls, NCBI Bookshelf
Peer-reviewed clinical reference on insomnia diagnosis and treatment.
- HPRA (Ireland) — Zimovane (zopiclone) 7.5 mg film-coated tablets
A current EU national authorisation for zopiclone (Irish medicines regulator), with its SmPC: indication, duration limit, contraindications, interactions, side effects.
- Modafinil — StatPearls, NCBI Bookshelf
Peer-reviewed clinical pharmacology and licensed indications.
- EMA — Modafinil referral
The EU-wide review that restricted modafinil to treating narcolepsy.
- EMA — PRAC signal on modafinil and birth defects (April 2019): new product information wording
The 2019 EU safety review that changed modafinil's product information to say it should not be used during pregnancy, because it is suspected to cause congenital malformations.
Health guides
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