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Condition guide

Nerve Pain

Nerve pain, also called neuropathic pain, is caused by damage to or irritation of the nerves rather than an injury to tissue. It is often described as burning, shooting, stabbing or tingling, and can be ongoing or come in sudden waves. It differs from ordinary pain and frequently needs a different approach to treatment.

Reviewed by the Kam4eu Pharmacy Team on 13 August 2026 · Next review August 2027

Recognising the signs

  • Burning, shooting or stabbing sensations, often in the hands, feet or legs
  • Tingling, prickling or a "pins and needles" feeling
  • Pain triggered by light touch, such as clothing or bedsheets
  • Numbness or reduced sensation in the affected area
  • Pain that is worse at night or disturbs sleep

Common causes

  • Diabetes, a common cause of nerve damage (diabetic neuropathy)
  • Shingles, which can lead to lingering nerve pain
  • Nerve compression, such as a trapped or pinched nerve
  • Injury or surgery affecting the nerves
  • Certain conditions such as multiple sclerosis
  • Excessive alcohol or some vitamin deficiencies
  • Side effects of some medicines, including certain chemotherapy treatments

Treatment options we stock

Nerve pain often does not respond well to ordinary painkillers, so specific medicines such as pregabalin and gabapentin are commonly used to calm overactive nerve signals. These are controlled medicines that should be taken exactly as prescribed, and the dose is usually adjusted gradually by a doctor. They must never be stopped suddenly, as this can cause withdrawal effects, so always reduce them under medical supervision. Read the patient information leaflet and discuss any other medicines or conditions with your doctor.

Pregabalin
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Lifestyle & self-care support

  • Manage any underlying condition, such as keeping blood sugar well controlled in diabetes
  • Stay gently active, as movement can help some types of nerve pain
  • Limit alcohol, which can worsen nerve damage
  • Use relaxation, pacing and good sleep habits to cope with persistent pain
  • Try a TENS machine or physiotherapy if recommended by a professional
  • Seek support for low mood, which often accompanies long-term pain

How to choose & when to see a doctor

Nerve pain should be assessed by a doctor, who can look for an underlying cause and tailor treatment to your situation. Medicines used for nerve pain are controlled and need careful dosing and monitoring, so they should only be taken under medical guidance. Read the patient information leaflet, never stop these medicines abruptly, and tell your doctor if the pain changes or worsens.

Frequently asked questions

Why don't normal painkillers work for nerve pain?+

Nerve pain comes from faulty nerve signalling rather than tissue damage, so standard painkillers such as paracetamol or ibuprofen often have little effect. Medicines like pregabalin and gabapentin work differently, by calming the overactive nerve signals. A doctor can advise which approach suits your type of pain.

Why can't I stop nerve pain medication suddenly?+

Medicines such as pregabalin and gabapentin should never be stopped abruptly, as this can cause withdrawal effects. The dose is usually reduced gradually under a doctor's supervision. If you want to stop, speak to your doctor first and follow the patient information leaflet.

Is nerve pain permanent?+

It depends on the cause. Some nerve pain improves when the underlying problem is treated, such as relieving a trapped nerve or controlling diabetes, while other types are long-lasting and managed rather than cured. A doctor can give you a clearer picture based on your situation.

Are pregabalin and gabapentin addictive?+

These are controlled medicines and can carry a risk of dependence, which is why they are prescribed carefully and taken exactly as directed. They should not be stopped suddenly or used in higher amounts than advised. Always follow your doctor's guidance and the patient information leaflet.

When should I see a doctor about nerve pain?+

See a doctor if you have persistent burning, shooting or tingling pain, numbness, or pain triggered by light touch, especially if it disturbs your sleep or daily life. Identifying the cause is important for effective treatment. Sudden severe symptoms, weakness or loss of function should be assessed promptly.

Nerve Pain health guides

Carisoprodol 500mg (Pain-O-Soma): uses, risks and the honest rules

Summary: carisoprodol 500mg — sold as Pain-O-Soma 500 — is a prescription-strength muscle relaxant for short-course treatment of acute muscle pain. It works, but it demands respect: it's for days-to-weeks, not months; it causes drowsiness; it must never be mixed with alcohol; and it carries genuine dependence potential. Here's the honest guide.

Read guide

Pain-O-Soma (carisoprodol): uses, dosage and how the muscle relaxer works

Summary: Pain-O-Soma is a brand of carisoprodol, a muscle relaxant for short-term relief of acute muscle and skeletal pain. Usual dose 250–350mg three times daily and at bedtime, for 2–3 weeks only. Here's how it works, the dosage, side effects and safety rules.

Read guide

Carisoprodol as a muscle relaxer: when it helps and when it doesn't

Summary: carisoprodol is a centrally-acting muscle relaxant best for short-term acute muscle pain — strains, spasms and injuries — alongside rest and physiotherapy. It's not for chronic pain or long-term use. Here's when it genuinely helps and the safer alternatives to consider.

Read guide

Pregabalin for nerve pain: how it works, dosage and what to expect

Summary: pregabalin (Lyrica) treats nerve (neuropathic) pain by calming overactive nerve signals. It's started low and increased gradually, taken daily, and takes a week or two to build its full effect. Here's how it works, the dosage, side effects and safety rules.

Read guide

Important: This information is general and not a substitute for medical advice. Always read the patient information leaflet supplied with your medicine and consult a doctor or pharmacist before starting treatment.