
Nervigesic 300mg — Pregabalin Capsules
Pregabalin
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KAM4U10Nervigesic 450mg: pregabalin 450 mg capsules, larger than any Lyrica capsule; only on a doctor's explicit instruction.
| Active ingredient & strength | Pregabalin 450 mg |
|---|---|
| Format | Capsule |
| Legal status | Prescription-only medicine in the EU/EEA |
| EU reference medicine | Lyrica — EMA product information (EPAR) |
| Price | From €35.00 (1 Strip/15 pills) · from €2.00 per pill (10 Strip/150 pills) |
| Delivery | 3–5 working days to most EU/EEA countries (2–7 by country) |
| Availability | In stock |
Generic Pregabalin — Nervigesic 450mg — Pregabalin Capsules. Available in multiple pack sizes.
Price range
Dispatched within one working day of payment
Pack size & pricing
3 · click to add
€2.33 per unit
€35.00
€2.20 per unit
€165.00
€2.00 per unit
€300.00
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Sealed manufacturer blisters or sachets with the batch number and expiry date printed, and the patient information leaflet in every box.
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Tracked shipping on every parcel. If a parcel is lost, we investigate with the courier and resolve it with a replacement shipment or another appropriate solution (see our delivery policy).
Discreet end to end
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Order & pay — order and payment confirmed by email
We pack — sealed packs, plain outer box
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Delivered — 3–5 working days to most EU/EEA countries (2–7 by country), nothing on the outside
Nervigesic 450mg: pregabalin 450 mg capsules, larger than any Lyrica capsule; only on a doctor's explicit instruction.
Part of our Pregabalin range.
Nervigesic 450mg contains 450 mg of pregabalin per capsule. In the EU, pregabalin (as Lyrica) is authorised for neuropathic pain, as add-on treatment for partial seizures and for generalised anxiety disorder, and it is a prescription-only medicine in the EU/EEA. The Lyrica product information sets a daily total of 150 to 600 mg, split into two or three doses and adjusted by the prescriber in stages, and its largest capsule is 300 mg, so a single 450 mg capsule is more than any one Lyrica dose. Nervigesic has no EU marketing authorisation, so no EU authority has assessed it against Lyrica. This strength is only for a doctor's explicit instruction as part of an established treatment plan; Nervigesic 150mg and the 300 mg capsules contain less.
Like all pregabalin, Nervigesic 450mg is absorbed rapidly — peak blood levels arrive around an hour after a dose — yet meaningful relief from nerve pain builds gradually with regular use. The leaflet notes that improvement may begin within the first week, with full benefit typically developing over one to two weeks of steady dosing. Patients on 450mg have usually been taking pregabalin for some time, so the question is less about onset and more about maintaining stable levels: take doses on schedule and do not skip days. Stopping a dose this high abruptly is particularly likely to cause withdrawal effects, so any change must be a supervised taper.
Only the amount of pregabalin per capsule. Side effects — dizziness, sedation, weight gain, blurred vision — become more likely as the dose rises, and a 450 mg capsule is larger than any single Lyrica dose. The 300 mg capsules — Nervigesic 300mg, Pregagesic 300, Neuro Seliron 300mg and Pregacare 300mg — contain the largest Lyrica capsule strength. Use Nervigesic 450mg only if your prescriber has set your regimen at this level; never raise the dose yourself.
Follow the leaflet and your prescriber's schedule precisely; pregabalin can be taken with or without food. Alcohol is strictly off the table — combined with high-dose pregabalin it can cause profound sedation and dangerous respiratory depression. Avoid driving until you know your response, and be alert for swelling, mood changes, or unusual drowsiness, reporting them to your doctor promptly. Dependence risk is real and dose-related, so anyone on this strength should have regular medical reviews. Never lend capsules to anyone, and plan any dose reduction as a gradual, doctor-led taper.
High-strength medicines call for extra checks on the pack. Nervigesic 450mg arrives factory-sealed with the batch number and expiry visible on both blister and box, and the manufacturer's patient leaflet enclosed so you can check the warnings yourself. Packs start at €35.00 for 1 Strip / 15 pills. Orders are dispatched within one working day of payment in plain, unbranded packaging, with tracking on every parcel; standard delivery takes 3–5 working days to most EU and EEA countries (2–7 by country) and is free over €110.
Pregabalin's side effects become more likely as the dose rises, so expect them to be more pronounced at 450 mg than at 150 mg or 300 mg. Common effects include dizziness, sleepiness, blurred or double vision, dry mouth, constipation, increased appetite with weight gain, and swollen ankles or hands. Unsteadiness and slowed reactions are frequent enough that driving should be avoided until you know your response. Rare but serious reactions demand immediate medical help: swelling of the face, tongue or throat, difficulty breathing, severe blistering rash, new or worsening depression, or thoughts of self-harm. Because sedation is dose-dependent, never stack Nervigesic 450mg with alcohol, opioids, or sleeping tablets — the combination can dangerously suppress breathing.
This is a high-strength medicine with genuine dependence potential, only for a doctor's explicit instruction. Do not take it if you are allergic to pregabalin. Avoid it if you have a history of substance or alcohol dependence, as pregabalin misuse risk is well documented. People with breathing problems (COPD, sleep apnoea), significant kidney impairment, or heart failure need medical assessment first — kidney disease in particular requires dose reduction because pregabalin is renally cleared. Do not combine with alcohol, opioids, benzodiazepines, or zopiclone-type sleeping pills. The elderly are especially vulnerable to falls and confusion at this strength. Pregnant or breastfeeding women should only use pregabalin on explicit medical advice.
Keep Nervigesic 450mg below 25–30°C in a dry spot away from sunlight and steam — avoid bathrooms and car glove boxes. Leave every capsule sealed in its original blister until use, and store the pack where children cannot reach it; a 450mg capsule is a serious overdose risk for a child. Authenticity checks: the blister foil should be fully sealed with no punctured pockets, the strip must show a printed batch number and expiry date, the outer carton should be crisp and untampered with matching details, and the pack should contain the manufacturer's patient leaflet. Discard anything that fails these checks.
Current prices: 1 Strip / 15 pills for €35.00 (€2.33 per pill), 5 Strip / 75 pills for €165.00 (€2.20 per pill) and 10 Strip / 150 pills for €300.00 (€2.00 per pill). Buying 10 Strip / 150 pills works out 14% cheaper per pill than the smallest pack. That only matters if 450 mg is actually your prescribed dose — price is never a reason to choose a higher strength.
General information about the active ingredient in Nervigesic 450mg — Pregabalin Capsules.
See the full Pregabalin guide & all Pregabalin productsPregabalin is a prescription-only medicine in the EU/EEA and the active substance of Lyrica. Its EU product information authorises it in adults for peripheral and central neuropathic (nerve) pain, as add-on treatment for partial seizures, and for generalised anxiety disorder. It can cause dependence, even at therapeutic doses, so it should be used only under medical supervision.
Pregabalin is a gamma-aminobutyric acid (GABA) analogue, but it does not act directly on GABA receptors. It binds to an auxiliary subunit (the alpha-2-delta protein) of voltage-gated calcium channels in the central nervous system, which reduces the release of several excitatory neurotransmitters involved in pain signalling, seizure activity and anxiety. It is absorbed quickly, with peak blood levels within about an hour, and is removed from the body mainly unchanged through the kidneys.
Take pregabalin exactly as prescribed. The EU product information describes a daily dose range of 150 to 600 mg, given in two or three divided doses, usually started low and increased step by step over one to a few weeks depending on response and side effects; your doctor sets and adjusts your dose. It can be taken with or without food. People with reduced kidney function need a lower dose. Never stop suddenly: the EU product information recommends stopping gradually over at least one week.
Common (usually mild and temporary):
Stop and seek medical help if you experience:
Store in the original packaging out of the sight and reach of children, and do not use after the expiry date. The EU product information states no special storage conditions are required. Return unused medicine to a pharmacy for safe disposal.
Its EU product information authorises it in adults for peripheral and central neuropathic (nerve) pain, as add-on treatment for partial seizures with or without secondary generalisation, and for generalised anxiety disorder.
No. Withdrawal symptoms reported after stopping include insomnia, headache, nausea, anxiety, diarrhoea, flu-like symptoms, nervousness, depression, pain, sweating, dizziness and seizures. The EU product information recommends stopping gradually over at least one week.
Yes. The EU product information states that pregabalin can cause drug dependence, which may occur at therapeutic doses, and that cases of misuse and abuse have been reported. Take it only as prescribed and never share it.
Pregabalin can add to the effects of alcohol and other sedatives. With opioids there have been reports of respiratory failure, coma and deaths, and a study linked the combination to a higher risk of opioid-related death. Discuss any such use with your doctor.
The EU product information warns that use in the first trimester may cause major birth defects and that pregabalin should not be used in pregnancy unless clearly necessary. Women who could become pregnant must use effective contraception during treatment.
Gabapentin also acts on the nervous system and is authorised for peripheral neuropathic pain and epilepsy. Duloxetine is an antidepressant authorised for diabetic peripheral neuropathic pain, depression and anxiety. Pregabalin is the only one of the three authorised for central neuropathic pain. See the comparison table on this page.
Important: This information is general and not a substitute for medical advice. Always read the patient information leaflet supplied with your medicine and consult a doctor or pharmacist before use — especially if you have existing health conditions or take other medication.
The larger the pack, the lower the price per unit.
Nervigesic options that contain pregabalin alone, with their current list prices. A higher strength is not better value: the EU product information has a doctor set the dose by how the medicine works for you and how well you tolerate it.
| Nervigesic | From | Lowest per unit |
|---|---|---|
| Nervigesic 150mg150 mg · Capsule | €27.001 Strip/15 pills | €1.47 per pill |
| Nervigesic 300mg300 mg · Capsule | €33.001 Strip/15 pills | €1.87 per pill |
| Nervigesic 450mg (this page)450 mg · Capsule | €35.001 Strip/15 pills | €2.00 per pill |
Nervigesic 450mg — Pregabalin Capsules isn't stocked on European high-street pharmacy shelves — it's an imported generic, so buying happens online. Kam4eu ships sealed Nervigesic 450mg — Pregabalin Capsules from €35.00 (3 pack sizes, lower per-unit price on larger packs) to all 27 EU + 3 EEA countries. Orders dispatch within one working day of payment; standard delivery takes 3–5 working days to most EU/EEA countries (2–7 by country), free over €110.00.
Nervigesic 450mg — Pregabalin Capsules starts from €35.00. Several pack sizes are available — the larger the pack, the lower the per-unit price. European delivery is free on orders over €110, otherwise €20 standard (3–5 working days to most countries, 2–7 by country).
Orders ship in plain, unbranded packaging from our European fulfilment hub, usually within one working day of payment clearing. Standard delivery reaches all 27 EU + 3 EEA countries in 3–5 working days to most of them (2–7 depending on the country); express (1–2 working days) is also available. For EU orders, VAT and duties are settled at checkout via IOSS, so there are no surprise bills on arrival.
The active ingredient in Nervigesic 450mg — Pregabalin Capsules is Pregabalin. Always read the patient information leaflet and consult a doctor or pharmacist before first use.
Choose your method at checkout: secure bank/SEPA transfer or PayPal. You'll receive clear payment confirmation by email, and we dispatch within one working day of payment clearing.
Yes. Every order ships in plain, unbranded outer packaging — nothing on the outside indicates the contents or the pharmacy.
No. Pain severity does not change how pregabalin is prescribed: the Lyrica product information sets a daily total of 150 to 600 mg, split into two or three doses and adjusted by the prescriber in stages. Higher doses sharply raise the risk of severe dizziness, sedation and falls. Discuss your pain with your prescriber.
The Lyrica product information sets 600 mg a day as the maximum, divided into two or three doses as your doctor directs. A 450 mg capsule is larger than any single Lyrica dose. Never combine strengths or take extra capsules beyond what your prescriber has set.
Pregabalin's common side effects — dizziness, drowsiness, blurred vision, weight gain, and peripheral swelling — are dose-related, so they occur more often and more intensely at 450mg than at 150mg or 300mg. If side effects are hard to tolerate, tell your doctor; a dose adjustment may help. Never stop abruptly.
No. Stopping high-dose pregabalin abruptly commonly causes withdrawal symptoms including insomnia, headache, nausea, anxiety, and sweating, and can provoke seizures in epilepsy patients. Your doctor should set a gradual tapering schedule, usually over at least a week and often longer at this strength.
Current prices: 1 Strip / 15 pills for €35.00 (€2.33 per pill), 5 Strip / 75 pills for €165.00 (€2.20 per pill) and 10 Strip / 150 pills for €300.00 (€2.00 per pill). Buying 10 Strip / 150 pills works out 14% cheaper per pill than the smallest pack. We ship sealed packs with batch and expiry details. Orders are dispatched within one working day of payment in plain, unbranded packaging, with tracking on every parcel; standard delivery takes 3–5 working days to most EU and EEA countries (2–7 by country) and is free over €110.
No — and at this strength the warning matters most. Alcohol amplifies pregabalin's sedation and can slow breathing to a dangerous degree when combined with a 450mg dose. Skip alcohol completely during treatment, and tell your prescriber if you drink regularly or have ever had an alcohol problem.
No. Opening a capsule and estimating part of the powder gives an unreliable dose. If you need a different dose, ask your doctor to prescribe the correct strength.
Pregabalin's half-life is roughly 6 hours with healthy kidneys, so a 450mg dose is largely cleared within one to two days. Impaired kidney function extends this considerably. Next-day drowsiness is possible at this strength, so do not drive or operate machinery until you feel fully alert.
Pregabalin is a prescription medicine across the EU, and in several countries it is additionally a controlled substance. It is your responsibility to know your country's rules and to use this medicine only under medical direction. We ship discreetly, but legality depends on your local regulations.
Pregabalin often needs one to two weeks of consistent dosing before nerve-pain or anxiety benefits are fully felt. Do not double up doses if relief seems slow. If there is no meaningful improvement after a few weeks, go back to your doctor rather than increasing the dose yourself.
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Reviewed by the Kam4eu editorial teamMedicine information reviewed 13 August 2026Next review due 13 August 2027
Sources for the medical information on this page
This page is general product and medicine information, not a prescription or a substitute for medical advice. Always read the patient information leaflet supplied with your medicine, and speak to a doctor or pharmacist before starting Nervigesic 450mg — especially if you take other medicines or have a heart, liver or kidney condition.