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Antibiotics

Bactrim DS

Bactrim DS: sulfamethoxazole + trimethoprim double-strength tablets, an antibiotic for infections a doctor has confirmed; prescription-only.

Key facts: Bactrim DS

Active ingredientSulfamethoxazole + Trimethoprim
FormatTablet
Legal statusPrescription-only medicine in the EU/EEA
PriceFrom €41.00 (20 pills) · from €1.80 per pill (100 pills)
Delivery3–5 working days to most EU/EEA countries (2–7 by country)
AvailabilityIn stock

Generic Sulfamethoxazole + Trimethoprim — Bactrim DS. Available in multiple pack sizes.

Price range

€41.00–€180.00
4 pack sizes available · Active ingredient: Sulfamethoxazole + Trimethoprim

Dispatched within one working day of payment

Pack size & pricing

4 · click to add

  • 20 pills

    €2.05 per unit

    €41.00

  • 30 pills

    €2.00 per unit

    €60.00

  • 50 pillsSave 7%

    €1.90 per unit

    €95.00

  • 100 pillsSave 12%

    €1.80 per unit

    €180.00

  • Secure payment
  • Discreet packaging
  • 3–5 working days
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Why buyers trust this order

Sealed manufacturer packs

Sealed manufacturer blisters or sachets with the batch number and expiry date printed, and the patient information leaflet in every box.

Tracked, with a lost-parcel policy

Tracked shipping on every parcel. If a parcel is lost, we investigate with the courier and resolve it with a replacement shipment or another appropriate solution (see our delivery policy).

Discreet end to end

Plain unbranded box, neutral sender, and a bank statement that shows only your order reference — never a product name.

A person answers, 7 days a week

Questions about ordering, delivery or payment are answered by a person on WhatsApp & Telegram, within our opening hours.

What happens after you order

  1. Order & pay — order and payment confirmed by email

  2. We pack — sealed packs, plain outer box

  3. Dispatched within 1 working day of payment — tracking number emailed

  4. Delivered — 3–5 working days to most EU/EEA countries (2–7 by country), nothing on the outside

About Bactrim DS

Bactrim DS: sulfamethoxazole + trimethoprim double-strength tablets, an antibiotic for infections a doctor has confirmed; prescription-only.

Bactrim DS: pack and delivery facts

  • Active ingredients: Sulfamethoxazole and Trimethoprim; no EU product information covers the combination.
  • 4 pack sizes to choose from, with a lower per-unit price on the larger packs.
  • Plain, unbranded packaging — nothing on the outside indicates the contents.
  • Delivered to all 27 EU + 3 EEA countries: 3–5 working days to most EU/EEA countries (2–7 by country).

Part of our Antibiotics range.

What is Bactrim DS?

Bactrim DS combines two antibiotics — sulfamethoxazole and trimethoprim — in a single double-strength (DS) tablet. The pairing blocks two consecutive steps in bacterial folate production, which is why the combination works against organisms that resist either ingredient alone. Its uses include urinary tract infections, certain respiratory and skin infections, and travellers' diarrhoea when the bacteria are known to be susceptible. It is also a standard choice for people allergic to penicillins, since it belongs to a completely different drug class from Amoxicillin 500mg. Bactrim DS should only be used for a doctor-confirmed bacterial infection — it does nothing against viruses such as colds or flu.

How long does Bactrim DS take to work?

How quickly symptoms ease varies by infection type and severity, and feeling better early is not a reason to stop: courses described in the leaflet typically run several days to two weeks depending on what is being treated, and stopping early lets surviving bacteria regrow — sometimes with resistance. Each dose maintains antibacterial levels for roughly half a day, which is why the leaflet describes twice-daily dosing at evenly spaced intervals. If symptoms have not improved after three days, or worsen at any point, contact a doctor rather than extending the course yourself.

Bactrim DS vs amoxicillin — what is the difference?

Bactrim DS and amoxicillin are different drug classes for different situations, and the right one depends on the infection and your allergy history. Amoxicillin, available here as Amoxicillin 250mg, Amoxicillin 500mg, Amoxicillin 650mg and Amoxicillin 1000mg, is a penicillin often preferred for ear, throat, dental and chest infections. Bactrim DS is frequently chosen for urinary infections and for penicillin-allergic patients. It is not suitable if you are allergic to sulfa drugs. Because the choice is diagnosis-driven, a doctor or pharmacist should confirm which one fits your infection before you order.

What should you know before taking Bactrim DS?

Follow the patient leaflet and your doctor's instructions, and finish the course you were prescribed even once you feel well. The leaflet covers fluid intake during treatment, because the sulfamethoxazole component can crystallise in concentrated urine, and sun exposure, because sulfa antibiotics can increase sun sensitivity. Tell your doctor about all other medicines, particularly blood thinners, methotrexate, diuretics and potassium-affecting drugs, which interact with trimethoprim. Bactrim DS is not appropriate in late pregnancy or with significant kidney disease — check first. Our amoxicillin uses and safety guide covers antibiotic basics that apply here too.

Why buy Bactrim DS from Kam4eu?

Every box of Bactrim DS we ship is sealed manufacturer stock with the batch number and expiry date printed on the blister and carton, plus the patient information leaflet inside. Orders are dispatched within one working day of payment in plain, unbranded packaging, with tracking on every parcel; standard delivery takes 3–5 working days to most EU and EEA countries (2–7 by country) and is free over €110. Packs start at €41.00 for 20 pills.

What are the side effects of Bactrim DS?

Bactrim DS (sulfamethoxazole + trimethoprim) is generally well tolerated, but like every antibiotic it can cause side effects. The most common are nausea, vomiting, loss of appetite, mild diarrhoea and skin rash. Some people notice headache or increased sensitivity to sunlight, so use sun protection during a course. Rare but serious reactions need urgent attention: a spreading blistering rash or peeling skin (possible Stevens-Johnson syndrome), unexplained bruising or bleeding, severe watery or bloody diarrhoea, yellowing of the skin or eyes, or signs of high potassium such as muscle weakness and irregular heartbeat — stop the tablets and seek medical help immediately. Side effects become more likely at higher doses and with longer courses, which is why you should never extend a course on your own.

Who should not take Bactrim DS?

Do not take Bactrim DS if you are allergic to sulfamethoxazole, trimethoprim or any other sulfonamide (sulfa) medicine — sulfa allergy is common and reactions can be severe. It is also unsuitable for people with serious liver damage, severe kidney impairment that is not being monitored, certain blood disorders such as megaloblastic anaemia caused by folate deficiency, and in late pregnancy or while breastfeeding a newborn. Tell a doctor first if you take warfarin, methotrexate, ACE inhibitors or potassium-sparing diuretics (risk of high potassium), phenytoin, or diabetes medicines like glibenclamide, because Bactrim DS interacts with all of these. Elderly patients and anyone with G6PD deficiency should only use it under medical supervision.

How should you store Bactrim DS and check it's genuine?

Keep Bactrim DS in its original blister strip, in a cool, dry place below 25°C, away from direct sunlight and bathroom humidity. Do not pop tablets out in advance — the foil protects them from moisture. Always store medicines out of sight and reach of children. To check your pack is genuine: the blister should be fully sealed with no lifted foil, each strip should carry a printed batch number and expiry date that match the outer carton, the box should arrive intact and uncrushed, and a patient information leaflet should be included. If anything looks tampered with, do not take the tablets — contact us first.

What does Bactrim DS cost? Price per tablet explained

Current prices: 20 pills for €41.00 (€2.05 per pill), 30 pills for €60.00 (€2.00 per pill), 50 pills for €95.00 (€1.90 per pill) and 100 pills for €180.00 (€1.80 per pill). Buying 100 pills works out 12% cheaper per pill than the smallest pack. Only order what a prescriber has actually recommended, though — antibiotics should be bought for a defined course, not stockpiled indefinitely.

About Sulfamethoxazole + Trimethoprim

General information about the active ingredient in Bactrim DS.

See the full Sulfamethoxazole + Trimethoprim guide & all Sulfamethoxazole + Trimethoprim products

What is Sulfamethoxazole + Trimethoprim?

Sulfamethoxazole with trimethoprim, often called co-trimoxazole (and known by brand names such as Bactrim), is a combination antibiotic that pairs two active ingredients in a fixed ratio. It is prescribed for certain bacterial infections, including some urinary tract infections and particular chest infections, and has an established role in preventing and treating a type of pneumonia (Pneumocystis pneumonia) in vulnerable people. It is effective only against susceptible bacteria, not viruses.

How it works

The two ingredients act on the same bacterial pathway at different steps. Bacteria need to make folic acid (folate) to build DNA and multiply. Sulfamethoxazole blocks an early step in folate production, while trimethoprim blocks a later step. By interrupting the pathway at two points, the combination has a stronger effect on susceptible bacteria than either drug alone. Human cells obtain folate from the diet and do not rely on this pathway, allowing the medicine to act more selectively.

How to take it

Take co-trimoxazole exactly as prescribed and read the patient information leaflet carefully. It comes as tablets and an oral liquid. It is generally recommended to take it with a meal or snack and to drink plenty of fluids during treatment to help protect the kidneys. Take doses at evenly spaced times and complete the full course even if you feel better, to help fully clear the infection and limit antibiotic resistance.

Side effects

Common (usually mild and temporary):

  • Nausea or vomiting
  • Diarrhoea
  • Loss of appetite
  • Skin rash or itching
  • Headache
  • Sore or inflamed mouth or tongue

Stop and seek medical help if you experience:

  • Signs of a severe allergic reaction such as swelling of the face, lips, tongue or throat, breathing difficulty, or collapse — seek emergency care
  • Severe, blistering or peeling skin rashes, or sores in the mouth, eyes or genitals — stop and get urgent help
  • Signs of a blood disorder such as unexplained bruising or bleeding, persistent sore throat, high fever or extreme tiredness
  • Yellowing of the skin or eyes, severe stomach pain, or other signs of liver problems
  • Severe or persistent watery or bloody diarrhoea during or after treatment

Safety & who should not take it

  • Tell your doctor if you are allergic to sulfonamide (sulfa) medicines, trimethoprim or other antibiotics, as serious allergic reactions can occur.
  • Inform your doctor of any kidney or liver problems, blood disorders, folate deficiency, asthma, or a deficiency of the enzyme G6PD before starting.
  • Generally avoided in pregnancy and in very young infants; tell your doctor if you are pregnant, planning a pregnancy or breastfeeding.
  • List all other medicines, as co-trimoxazole interacts with several drugs, including some blood thinners, diabetes medicines and water tablets (diuretics).
  • Drink plenty of fluids during treatment and tell your doctor if you produce much less urine than usual.
  • Use only for the infection it was prescribed for, and never share it, to help limit antibiotic resistance.
  • Return any unused or out-of-date medicine to a pharmacy for safe disposal.

Storage

Store in the original packaging below 25°C, protected from light and moisture, out of the sight and reach of children. Follow any specific shelf-life instructions for the oral liquid. Do not use after the expiry date.

Frequently asked questions

Why is co-trimoxazole two medicines in one?+

Combining sulfamethoxazole and trimethoprim blocks the same bacterial folate pathway at two separate steps, giving a stronger effect against susceptible bacteria than either ingredient alone.

Why should I drink plenty of water with it?+

Drinking adequate fluids helps keep urine flowing and supports the kidneys during treatment. Your doctor or pharmacist can advise how much is appropriate for you.

Can I stop taking it once I feel better?+

No. Finish the full course as prescribed, even if symptoms improve, to help clear the infection completely and reduce the risk of antibiotic resistance.

Important: This information is general and not a substitute for medical advice. Always read the patient information leaflet supplied with your medicine and consult a doctor or pharmacist before use — especially if you have existing health conditions or take other medication.

Pack sizes & pricing

The larger the pack, the lower the price per unit.

  • 20 pills€41.00
  • 30 pills€60.00
  • 50 pills€95.00
  • 100 pills€180.00

Delivery & discreet packaging

  • Delivery to all 27 EU + 3 EEA countries: 3–5 working days to most EU/EEA countries (2–7 by country). Free on orders over €110.00, otherwise €20.00 standard.
  • Dispatched within one working day of payment clearing, with a confirmation email.
  • Plain, unbranded outer packaging — nothing on the outside indicates the contents.
  • VAT included at checkout. IOSS covers EU deliveries, so EU orders have no customs bill on arrival; Iceland, Liechtenstein and Norway handle their own import formalities.

Where to buy Bactrim DS in Europe

Bactrim DS isn't stocked on European high-street pharmacy shelves — it's an imported generic, so buying happens online. Kam4eu ships sealed Bactrim DS from €41.00 (4 pack sizes, lower per-unit price on larger packs) to all 27 EU + 3 EEA countries. Orders dispatch within one working day of payment; standard delivery takes 3–5 working days to most EU/EEA countries (2–7 by country), free over €110.00.

  • Pay in EUR — SEPA bank transfer or PayPal. For bank transfer, use only your order reference so your statement stays discreet.
  • Plain, unbranded packaging with tracked delivery. VAT is included at checkout; IOSS covers EU deliveries, so EU orders have no customs bill on arrival.
  • Sealed manufacturer blisters or sachets with batch number and expiry, plus the patient information leaflet in every box.
  • Site and order emails in 24 European languages. Prices are in euros (EUR).

Common questions about Bactrim DS

How much does Bactrim DS cost?+

Bactrim DS starts from €41.00. Several pack sizes are available — the larger the pack, the lower the per-unit price. European delivery is free on orders over €110, otherwise €20 standard (3–5 working days to most countries, 2–7 by country).

How is Bactrim DS delivered across Europe?+

Orders ship in plain, unbranded packaging from our European fulfilment hub, usually within one working day of payment clearing. Standard delivery reaches all 27 EU + 3 EEA countries in 3–5 working days to most of them (2–7 depending on the country); express (1–2 working days) is also available. For EU orders, VAT and duties are settled at checkout via IOSS, so there are no surprise bills on arrival.

What is the active ingredient in Bactrim DS?+

Bactrim DS contains two active ingredients: Sulfamethoxazole and Trimethoprim. Always read the patient information leaflet and consult a doctor or pharmacist before first use.

How do I pay for my order?+

Choose your method at checkout: secure bank/SEPA transfer or PayPal. You'll receive clear payment confirmation by email, and we dispatch within one working day of payment clearing.

Is Bactrim DS discreetly packaged?+

Yes. Every order ships in plain, unbranded outer packaging — nothing on the outside indicates the contents or the pharmacy.

What does the DS in Bactrim DS mean?+

DS stands for double strength. A Bactrim DS tablet contains 800mg sulfamethoxazole and 160mg trimethoprim — twice the amount in a regular-strength Bactrim tablet. This lets many adult regimens work with one tablet per dose instead of two. Confirm with a doctor that the DS strength matches the regimen intended for your infection.

Can I take Bactrim DS if I'm allergic to penicillin?+

Bactrim DS contains no penicillin, so a penicillin allergy alone does not rule it out; whether it suits you is your doctor's decision. It must not be taken if you are allergic to sulfonamide (sulfa) medicines. If you have any allergy history, mention it to a doctor or pharmacist before starting, and stop immediately if a rash develops.

Does Bactrim DS work for a urinary tract infection?+

Trimethoprim-sulfamethoxazole is a long-established treatment for uncomplicated urinary tract infections where local bacteria remain susceptible to it. Resistance rates vary by country, so it is not guaranteed to work everywhere. A doctor can judge whether it suits your case; if symptoms persist beyond two to three days of treatment, seek medical review.

What are the most common side effects of Bactrim DS?+

Nausea, loss of appetite, and skin rash are the most frequently reported effects. Any rash deserves attention with sulfa antibiotics: stop the tablets and contact a doctor promptly, because rare but serious skin reactions can begin this way. Increased sun sensitivity is also common — read the full leaflet before your first dose.

Can I take Bactrim DS with alcohol?+

Alcohol can add to nausea, dizziness and dehydration during treatment. The package leaflet covers alcohol; ask your doctor or pharmacist how it applies to you.

Should Bactrim DS be taken with food?+

The package leaflet explains how to take Bactrim DS, including with food and fluids; drinking enough during the course matters because the sulfamethoxazole component can crystallise in concentrated urine. Follow the leaflet and your doctor's instructions.

What if Bactrim DS doesn't work the first time?+

If your symptoms have not started improving after two to three days of correct dosing, do not simply take more. The bacteria may be resistant to sulfamethoxazole-trimethoprim, or the diagnosis may need reviewing. See a doctor — they may switch you to a different antibiotic class rather than repeating the same course.

How long does Bactrim DS stay in your system?+

Trimethoprim has a half-life of roughly 8–10 hours and sulfamethoxazole about 10 hours in healthy adults, so most of a dose is cleared within two to three days of your last tablet. Clearance is slower if your kidneys are impaired, which is why doses are reduced in kidney disease.

Does Bactrim DS expire, and can I use old tablets?+

Yes — every blister carries a printed expiry date, typically two to three years from manufacture. Do not use tablets past that date: potency declines and the medicine may not clear your infection, which encourages resistance. Dispose of expired antibiotics at a pharmacy rather than in household waste or down the sink.

Health guides

Guides & related reading for Bactrim DS

6 research-backed guides — newest first.

Bactrim (Co-trimoxazole): A Guide to This Antibiotic

Read guide

Amoxicillin and alcohol: what actually happens if you drink

Read guide

Amoxicillin: uses, dosage and how to take this antibiotic correctly

Read guide

Amoxicillin: Uses, Safety and Why You Must Finish the Course

Read guide

Ivermectin: Its Established, Approved Uses Explained

Read guide

UTI Antibiotics: What to Know Before You Start

Read guide

Before you buy Bactrim DS

  • Read the patient information leaflet supplied with the product in full before first use.
  • Tell your doctor or pharmacist about any existing health conditions and other medicines you take, so they can check it is suitable for you.
  • Do not exceed the dose described in the leaflet, and never take more than one medicine for the same purpose at the same time.
  • Buy from a reputable source and check the packaging and leaflet are intact on arrival.
  • Keep all medicines out of the sight and reach of children.

Customer reviews

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  • Every review is checked by our team before it appears

Reviewed by the Kam4eu editorial teamMedicine information reviewed 13 August 2026Next review due 13 August 2027

Sources for the medical information on this page

This page is general product and medicine information, not a prescription or a substitute for medical advice. Always read the patient information leaflet supplied with your medicine, and speak to a doctor or pharmacist before starting Bactrim DS — especially if you take other medicines or have a heart, liver or kidney condition.

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