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Erectile Dysfunction

Avana 50

Avana 50: avanafil 50 mg, below the 100 mg dose the Spedra EPAR recommends; one dose a day at most.

Key facts: Avana 50

Active ingredient & strengthAvanafil 50 mg
FormatTablet
Legal statusPrescription-only medicine in the EU/EEA
EU reference medicineSpedra — EMA product information (EPAR)
EU dose limitAt most one dose in 24 hours
PriceFrom €20.00 (1 Strip/4 pills) · from €3.75 per pill (10 Strip/40 pills)
Delivery3–5 working days to most EU/EEA countries (2–7 by country)
AvailabilityIn stock

Generic Avanafil — Avana 50. Available in multiple pack sizes.

Price range

€20.00–€150.00
3 pack sizes available · Active ingredient: Avanafil

Dispatched within one working day of payment

Pack size & pricing

3 · click to add

  • 1 Strip/4 pills

    €5.00 per unit

    €20.00

  • 5 Strip/ 20 pillsSave 10%

    €4.50 per unit

    €90.00

  • 10 Strip/40 pillsSave 25%

    €3.75 per unit

    €150.00

  • Secure payment
  • Discreet packaging
  • 3–5 working days
Questions about ordering, delivery or payment? Message us on WhatsApp →

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Why buyers trust this order

Sealed manufacturer packs

Sealed manufacturer blisters or sachets with the batch number and expiry date printed, and the patient information leaflet in every box.

Tracked, with a lost-parcel policy

Tracked shipping on every parcel. If a parcel is lost, we investigate with the courier and resolve it with a replacement shipment or another appropriate solution (see our delivery policy).

Discreet end to end

Plain unbranded box, neutral sender, and a bank statement that shows only your order reference — never a product name.

A person answers, 7 days a week

Questions about ordering, delivery or payment are answered by a person on WhatsApp & Telegram, within our opening hours.

What happens after you order

  1. Order & pay — order and payment confirmed by email

  2. We pack — sealed packs, plain outer box

  3. Dispatched within 1 working day of payment — tracking number emailed

  4. Delivered — 3–5 working days to most EU/EEA countries (2–7 by country), nothing on the outside

Contains Avanafil; the EU-authorised reference medicine for it is Spedra. Is it legal? Read our honest answers →

About Avana 50

Avana 50: avanafil 50 mg, below the 100 mg dose the Spedra EPAR recommends; one dose a day at most.

What makes Avana 50 distinct

Avana 50 is the lowest-strength avanafil tablet. Avanafil is the newest of the PDE5 inhibitors used for erectile dysfunction, and the EU product information for avanafil (Spedra) lists 50mg among its authorised strengths.

It is taken about 15 to 30 minutes before sexual activity, according to the EU product information for Spedra, and works only with sexual arousal. A doctor decides which strength is right; the usual nitrate caution applies.

Avana 50: pack and delivery facts

  • Active ingredient: Avanafil. The EU-authorised reference medicine for avanafil is Spedra.
  • 3 pack sizes to choose from, with a lower per-unit price on the larger packs.
  • Plain, unbranded packaging — nothing on the outside indicates the contents.
  • Delivered to all 27 EU + 3 EEA countries: 3–5 working days to most EU/EEA countries (2–7 by country).

Part of our Erectile Dysfunction range.

What is Avana 50?

Avana 50 contains 50 mg of avanafil, the active ingredient of Spedra and the most recently authorised of the PDE5 inhibitors used in the EU for erectile dysfunction. The EU product information for Spedra recommends 100 mg and lets a doctor lower the dose to 50 mg or raise it to 200 mg, depending on how it works and how well it is tolerated; it also says men already taking alpha-blockers should initially be given this lowest dose. Avana has no EU marketing authorisation, and avanafil is a prescription-only medicine in the EU/EEA, so whether 50 mg suits you is a doctor's decision. For how the ED medicines compare, see our guide to ED medicines.

How long does Avana 50 take to work, and how long does it last?

The EU product information for Spedra says avanafil is taken as needed about 15 to 30 minutes before sexual activity (EMA: Spedra), compared with about one hour for sildenafil; tadalafil's product information describes an effect lasting up to 36 hours (Kamagra vs Cialis explains the difference). The Spedra product information gives no fixed duration of effect. It notes that taking avanafil with food may delay the start of its effect. Sexual arousal is still required for the tablet to work at all, and the one-dose-per-24-hours rule applies at every strength.

Avana 50 vs Avana 100 and Avana 200 — what is the difference?

Only the amount of avanafil. Avana 100 contains the 100 mg dose the Spedra product information recommends, and Avana 200 its 200 mg maximum. Headache, flushing and congestion become more frequent as the dose increases, and any change of strength is your doctor's decision, based on how the medicine works for you and how well you tolerate it. Our avanafil guide explains how the medicine works.

What should you know before taking Avana 50?

Read the leaflet before the first tablet; the EU product information allows one dose of avanafil a day at most. The Spedra product information says it is taken about 15 to 30 minutes before sexual activity, and that food may delay its effect. Alcohol can lower blood pressure further and makes erections harder on its own. Avanafil supports the physical mechanics of an erection but does not create desire; without arousal, nothing happens. Never combine it with nitrates, and tell your doctor about alpha-blockers, blood-pressure medicines and medicines such as ritonavir, ketoconazole or erythromycin. If it doesn't work as you expect, see a doctor — hormonal or circulation problems are worth ruling out, as our avanafil guide explains.

Why buy Avana 50 from Kam4eu?

Kam4eu supplies Avana 50 as a factory-sealed product with the batch number and expiry visible on the blister and the patient leaflet enclosed, so you can check what you receive. Orders are dispatched within one working day of payment in plain packaging with no pharmacy branding, with tracking on every parcel; standard delivery takes 3–5 working days to most EU and EEA countries (2–7 by country) and is free over €110. Packs start at €20.00 for 1 Strip / 4 pills.

What are the side effects of Avana 50?

Avana 50 shares the side-effect list of every avanafil tablet: common reactions listed in the leaflet can occur: headache, facial flushing, a blocked or stuffy nose, back pain and mild dizziness. These are usually mild and pass within hours. Rare but serious effects still apply at 50 mg: a painful erection lasting over four hours (priapism), sudden vision loss or dimming, sudden hearing loss or tinnitus, and chest pain during sexual activity. Any of these means stop the medicine and seek medical help straight away. If side effects trouble you, tell your doctor.

Who should not take Avana 50?

Even at this low strength, the absolute rule stands: never combine Avana 50 with nitrates (angina medicines like glyceryl trinitrate or isosorbide) or with poppers (amyl or butyl nitrite). Together they can drop blood pressure to dangerous levels. Use caution with alpha-blockers such as tamsulosin or doxazosin — timing and dose separation matter. Men with severe heart failure, unstable angina, a recent heart attack or stroke, very low or uncontrolled blood pressure, or significant liver or kidney disease need a doctor's clearance first. Avoid avanafil if sex itself has been judged unsafe for your heart, if you take strong CYP3A4 inhibitors like ritonavir or ketoconazole, or if you have previously reacted to avanafil.

How should you store Avana 50 and check it's genuine?

Store Avana 50 below 25–30 °C in a cool, dry spot, keeping tablets in their original sealed blister until the moment you take one. Avoid bathrooms and windowsills where heat and moisture degrade tablets, and keep the pack well out of children's reach. Authenticity checks take thirty seconds: the blister foil should be uniformly sealed with no punctures, the batch number and expiry date must be printed on both the blister strip and the outer box and should match, the box should contain a patient information leaflet, and the carton should arrive undamaged. Anything missing or tampered with — don't take it; contact us instead.

What does Avana 50 cost? Price per tablet explained

Current prices: 1 Strip / 4 pills for €20.00 (€5.00 per pill), 5 Strip / 20 pills for €90.00 (€4.50 per pill) and 10 Strip / 40 pills for €150.00 (€3.75 per pill). Buying 10 Strip / 40 pills works out 25% cheaper per pill than the smallest pack. Buy only what you will use before the printed expiry date.

About Avanafil

General information about the active ingredient in Avana 50.

See the full Avanafil guide & all Avanafil products

What is Avanafil?

Avanafil is a prescription-only medicine in the EU/EEA used to treat erectile dysfunction in adult men. It belongs to the class of medicines known as phosphodiesterase type 5 (PDE5) inhibitors and is the active substance of Spedra, the avanafil medicine authorised across the EU through the European Medicines Agency. Sexual stimulation is needed for it to work.

How it works

Avanafil is a highly selective, reversible inhibitor of the PDE5 enzyme. When sexual stimulation releases nitric oxide in the penis, blocking PDE5 lets cyclic guanosine monophosphate (cGMP) build up, which relaxes the smooth muscle and lets blood flow into the penile tissue to produce an erection. The EU product information states that avanafil has no effect without sexual stimulation. It is absorbed quickly: peak blood levels are reached roughly 30 to 45 minutes after a dose taken on an empty stomach.

How to take it

Avanafil is taken by mouth, as needed, approximately 15 to 30 minutes before sexual activity, at the dose your doctor prescribes. It must not be taken more than once a day. It can be taken with or without food, but the EU product information notes that taking it with food may delay the start of its effect. Your doctor may use a lower dose if you take certain other medicines or have mild to moderate liver problems. Always follow the patient information leaflet.

Side effects

Common (usually mild and temporary):

  • Headache
  • Flushing
  • Nasal and sinus congestion
  • Back pain

Stop and seek medical help if you experience:

  • An erection lasting 4 hours or more (priapism) — seek immediate medical help to avoid permanent damage
  • Sudden decrease or loss of vision in one or both eyes — stop taking it and see a doctor immediately
  • Sudden decrease or loss of hearing, sometimes with ringing in the ears or dizziness — stop taking it and get prompt medical attention
  • Chest pain during or after sexual activity
  • Fainting, or severe dizziness or light-headedness on standing

Safety & who should not take it

  • Must NOT be taken with any nitrate medicine for angina or with nitric-oxide donors such as amyl nitrite ('poppers'), or with riociguat, because of the risk of a dangerous fall in blood pressure.
  • Not to be used by men who have had a heart attack, stroke or life-threatening heart-rhythm problem in the last 6 months, or who have unstable angina, angina during sex, or moderate-to-severe heart failure.
  • Not to be used with very low (below 90/50 mmHg) or very high (above 170/100 mmHg) blood pressure, severe liver or severe kidney impairment, or after loss of vision in one eye from NAION.
  • Must not be combined with potent CYP3A4-inhibiting medicines such as ketoconazole, itraconazole, ritonavir or clarithromycin.
  • Alpha-blockers, other blood-pressure medicines and alcohol can each add to the blood-pressure-lowering effect and cause dizziness or fainting.
  • Avoid grapefruit juice within 24 hours before taking avanafil.
  • Do not combine with other PDE5 inhibitors or other erectile-dysfunction treatments — the combinations have not been studied.
  • Not indicated for women or for anyone under 18.

Storage

Store in the original packaging out of the sight and reach of children, and do not use after the expiry date. The EU product information states no special storage conditions are required.

Frequently asked questions

How quickly does avanafil work?+

The EU product information for Spedra says to take it approximately 15 to 30 minutes before sexual activity. In a clinical study some men had an erection sufficient for penetration as early as 20 minutes after a dose. Sexual stimulation is still needed, and response varies between men.

How long does avanafil last?+

The EU product information gives no fixed duration window for avanafil, unlike tadalafil's. It reports a terminal half-life of roughly 6 to 17 hours, which describes how the drug leaves the body rather than how long an erection response lasts. Do not take more than one dose a day.

Can avanafil be taken with food or alcohol?+

It can be taken with or without food, though food may delay the start of its effect. The EU product information advises against combining it with alcohol, because the two together increase the chance of low blood pressure, dizziness and fainting.

Which medicines must never be combined with avanafil?+

Nitrates for angina, nitric-oxide donors such as amyl nitrite ('poppers'), riociguat, and potent CYP3A4 inhibitors such as ketoconazole, itraconazole, ritonavir and clarithromycin. Tell your doctor about every medicine you take, including alpha-blockers and other blood-pressure medicines.

How is avanafil different from sildenafil and tadalafil?+

All three are PDE5 inhibitors. According to their EU product information, avanafil is taken about 15 to 30 minutes before sex, sildenafil about 1 hour before, and tadalafil at least 30 minutes before, with tadalafil showing a response up to 36 hours after the dose. The comparison table on this page lists the details.

Is generic avanafil the same as Spedra?+

Avanafil is the active substance in Spedra. A generic product contains the same active substance, but only medicines with an EU or national marketing authorisation have been assessed by a European regulator. Avanafil is prescription-only in the EU/EEA.

Important: This information is general and not a substitute for medical advice. Always read the patient information leaflet supplied with your medicine and consult a doctor or pharmacist before use — especially if you have existing health conditions or take other medication.

Pack sizes & pricing

The larger the pack, the lower the price per unit.

  • 1 Strip/4 pills€20.00
  • 5 Strip/ 20 pills€90.00
  • 10 Strip/40 pills€150.00

Delivery & discreet packaging

  • Delivery to all 27 EU + 3 EEA countries: 3–5 working days to most EU/EEA countries (2–7 by country). Free on orders over €110.00, otherwise €20.00 standard.
  • Dispatched within one working day of payment clearing, with a confirmation email.
  • Plain, unbranded outer packaging — nothing on the outside indicates the contents.
  • VAT included at checkout. IOSS covers EU deliveries, so EU orders have no customs bill on arrival; Iceland, Liechtenstein and Norway handle their own import formalities.

Avana prices by strength

Avana options that contain avanafil alone, with their current list prices. A higher strength is not better value: the EU product information has a doctor set the dose by how the medicine works for you and how well you tolerate it.

AvanaFromLowest per unit
Avana 50 (this page)50 mg€20.001 Strip/4 pills€3.75 per pill
Avana 100100 mg€23.001 Strip/4 pills€4.75 per pill
Avana 200200 mg€27.001 Strip/4 pills€5.00 per pill

Where to buy Avana 50 in Europe

Avana 50 isn't stocked on European high-street pharmacy shelves — it's an imported generic, so buying happens online. Kam4eu ships sealed Avana 50 from €20.00 (3 pack sizes, lower per-unit price on larger packs) to all 27 EU + 3 EEA countries. Orders dispatch within one working day of payment; standard delivery takes 3–5 working days to most EU/EEA countries (2–7 by country), free over €110.00. Unsure about the legal side? Our honest legality answers explains the brand-vs-ingredient distinction plainly.

  • Pay in EUR — SEPA bank transfer or PayPal. For bank transfer, use only your order reference so your statement stays discreet.
  • Plain, unbranded packaging with tracked delivery. VAT is included at checkout; IOSS covers EU deliveries, so EU orders have no customs bill on arrival.
  • Sealed manufacturer blisters or sachets with batch number and expiry, plus the patient information leaflet in every box.
  • Site and order emails in 24 European languages. Prices are in euros (EUR).

Common questions about Avana 50

How much does Avana 50 cost?+

Avana 50 starts from €20.00. Several pack sizes are available — the larger the pack, the lower the per-unit price. European delivery is free on orders over €110, otherwise €20 standard (3–5 working days to most countries, 2–7 by country).

How is Avana 50 delivered across Europe?+

Orders ship in plain, unbranded packaging from our European fulfilment hub, usually within one working day of payment clearing. Standard delivery reaches all 27 EU + 3 EEA countries in 3–5 working days to most of them (2–7 depending on the country); express (1–2 working days) is also available. For EU orders, VAT and duties are settled at checkout via IOSS, so there are no surprise bills on arrival.

What is the active ingredient in Avana 50?+

The active ingredient in Avana 50 is Avanafil. Always read the patient information leaflet and consult a doctor or pharmacist before first use.

How do I pay for my order?+

Choose your method at checkout: secure bank/SEPA transfer or PayPal. You'll receive clear payment confirmation by email, and we dispatch within one working day of payment clearing.

Is Avana 50 discreetly packaged?+

Yes. Every order ships in plain, unbranded outer packaging — nothing on the outside indicates the contents or the pharmacy.

Is Avana 50 strong enough to work?+

50 mg is one of the doses in the EU product information for Spedra, which recommends 100 mg and lets a doctor lower it to 50 mg or raise it to 200 mg; men already taking alpha-blockers should initially be given 50 mg. How a dose works differs between men, so whether 50 mg suits you is your doctor's decision.

Is Avana 50 suitable if I have never taken an ED medicine?+

That is your doctor's decision. The Spedra product information recommends 100 mg for most men and names 50 mg for some, such as men taking alpha-blockers. Speak to a doctor before starting any ED medicine, particularly if you have heart problems, take nitrates, or have other significant health conditions.

How quickly does Avana 50 start working?+

The EU product information for Spedra says avanafil is taken about 15 to 30 minutes before sexual activity, at any strength (EMA: Spedra), and that food may delay its effect. The tablet only works together with sexual arousal — it does not cause erections on its own.

Can I take two Avana 50 tablets to make 100 mg?+

No. Never change your dose by combining tablets — the maximum is one dose in any 24-hour period, and any change of dose is your doctor's decision.

What does Avana 50 cost and how is it delivered?+

Current prices: 1 Strip / 4 pills for €20.00 (€5.00 per pill), 5 Strip / 20 pills for €90.00 (€4.50 per pill) and 10 Strip / 40 pills for €150.00 (€3.75 per pill). Buying 10 Strip / 40 pills works out 25% cheaper per pill than the smallest pack. Orders are dispatched within one working day of payment in plain packaging with no pharmacy branding, with tracking on every parcel; standard delivery takes 3–5 working days to most EU and EEA countries (2–7 by country) and is free over €110.

Can I take Avana 50 with food?+

The Spedra product information says avanafil can be taken with or without food, but that taking it with food may delay the start of its effect. Grapefruit juice is best avoided, as it can raise avanafil levels. Your doctor and the package leaflet set how it applies to you.

What if Avana 50 doesn't work the first time?+

Don't take another tablet within 24 hours. Nerves, food, alcohol and a lack of arousal can all affect how avanafil works, as the package leaflet explains. If it doesn't work as you expect, talk to your doctor rather than changing the dose yourself.

How long does Avana 50 stay in your system?+

The EU product information gives avanafil's timing but no fixed duration of effect. Whatever the effect, wait a full 24 hours before any next dose.

Is Avana 50 legal to order online?+

Avanafil is a prescription-only medicine across the EU/EEA, Avana has no EU marketing authorisation, and rules on personal importation vary by country. Speak to a doctor and get a valid prescription first, and check your national regulations.

Does Avana 50 expire?+

Yes. Every blister and box carries a printed expiry date. Do not take tablets past that date, and keep them cool, dry and sealed in the original blister until then.

Health guides

Guides & related reading for Avana 50

6 research-backed guides — newest first.

Avanafil (Avana): How This PDE5 Inhibitor Works and When It Is Taken

Read guide

Avanafil vs Sildenafil: How the Two ED Tablets Compare

Read guide

“Liquid Viagra”: What People Actually Mean — and the Real Options

Read guide

The “Blue Salt Trick” for ED: Does It Actually Work?

Read guide

Why generic sildenafil and Cialis have 20 brand names

Read guide

Eroxon gel: availability, evidence and how it compares

Read guide

Before you buy Avana 50

  • Read the patient information leaflet supplied with the product in full before first use.
  • Tell your doctor or pharmacist about any existing health conditions and other medicines you take, so they can check it is suitable for you.
  • Do not exceed the dose described in the leaflet, and never take more than one medicine for the same purpose at the same time.
  • Buy from a reputable source and check the packaging and leaflet are intact on arrival.
  • Keep all medicines out of the sight and reach of children.

Customer reviews

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Reviews on Kam4eu come only from verified orders — never from us.

  • Buyers get a review link by email after their order ships
  • Verified-buyer reviews get the green badge
  • Every review is checked by our team before it appears

Reviewed by the Kam4eu editorial teamMedicine information reviewed 13 August 2026Next review due 13 August 2027

Sources for the medical information on this page

This page is general product and medicine information, not a prescription or a substitute for medical advice. Always read the patient information leaflet supplied with your medicine, and speak to a doctor or pharmacist before starting Avana 50 — especially if you take other medicines or have a heart, liver or kidney condition.

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