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KAM4U10Avana 50: avanafil 50 mg, below the 100 mg dose the Spedra EPAR recommends; one dose a day at most.
| Active ingredient & strength | Avanafil 50 mg |
|---|---|
| Format | Tablet |
| Legal status | Prescription-only medicine in the EU/EEA |
| EU reference medicine | Spedra — EMA product information (EPAR) |
| EU dose limit | At most one dose in 24 hours |
| Price | From €20.00 (1 Strip/4 pills) · from €3.75 per pill (10 Strip/40 pills) |
| Delivery | 3–5 working days to most EU/EEA countries (2–7 by country) |
| Availability | In stock |
Generic Avanafil — Avana 50. Available in multiple pack sizes.
Price range
Dispatched within one working day of payment
Pack size & pricing
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€5.00 per unit
€20.00
€4.50 per unit
€90.00
€3.75 per unit
€150.00
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Why buyers trust this order
Sealed manufacturer packs
Sealed manufacturer blisters or sachets with the batch number and expiry date printed, and the patient information leaflet in every box.
Tracked, with a lost-parcel policy
Tracked shipping on every parcel. If a parcel is lost, we investigate with the courier and resolve it with a replacement shipment or another appropriate solution (see our delivery policy).
Discreet end to end
Plain unbranded box, neutral sender, and a bank statement that shows only your order reference — never a product name.
A person answers, 7 days a week
Questions about ordering, delivery or payment are answered by a person on WhatsApp & Telegram, within our opening hours.
What happens after you order
Order & pay — order and payment confirmed by email
We pack — sealed packs, plain outer box
Dispatched within 1 working day of payment — tracking number emailed
Delivered — 3–5 working days to most EU/EEA countries (2–7 by country), nothing on the outside
Avana 50: avanafil 50 mg, below the 100 mg dose the Spedra EPAR recommends; one dose a day at most.
What makes Avana 50 distinct
Avana 50 is the lowest-strength avanafil tablet. Avanafil is the newest of the PDE5 inhibitors used for erectile dysfunction, and the EU product information for avanafil (Spedra) lists 50mg among its authorised strengths.
It is taken about 15 to 30 minutes before sexual activity, according to the EU product information for Spedra, and works only with sexual arousal. A doctor decides which strength is right; the usual nitrate caution applies.
Part of our Erectile Dysfunction range.
Avana 50 contains 50 mg of avanafil, the active ingredient of Spedra and the most recently authorised of the PDE5 inhibitors used in the EU for erectile dysfunction. The EU product information for Spedra recommends 100 mg and lets a doctor lower the dose to 50 mg or raise it to 200 mg, depending on how it works and how well it is tolerated; it also says men already taking alpha-blockers should initially be given this lowest dose. Avana has no EU marketing authorisation, and avanafil is a prescription-only medicine in the EU/EEA, so whether 50 mg suits you is a doctor's decision. For how the ED medicines compare, see our guide to ED medicines.
The EU product information for Spedra says avanafil is taken as needed about 15 to 30 minutes before sexual activity (EMA: Spedra), compared with about one hour for sildenafil; tadalafil's product information describes an effect lasting up to 36 hours (Kamagra vs Cialis explains the difference). The Spedra product information gives no fixed duration of effect. It notes that taking avanafil with food may delay the start of its effect. Sexual arousal is still required for the tablet to work at all, and the one-dose-per-24-hours rule applies at every strength.
Only the amount of avanafil. Avana 100 contains the 100 mg dose the Spedra product information recommends, and Avana 200 its 200 mg maximum. Headache, flushing and congestion become more frequent as the dose increases, and any change of strength is your doctor's decision, based on how the medicine works for you and how well you tolerate it. Our avanafil guide explains how the medicine works.
Read the leaflet before the first tablet; the EU product information allows one dose of avanafil a day at most. The Spedra product information says it is taken about 15 to 30 minutes before sexual activity, and that food may delay its effect. Alcohol can lower blood pressure further and makes erections harder on its own. Avanafil supports the physical mechanics of an erection but does not create desire; without arousal, nothing happens. Never combine it with nitrates, and tell your doctor about alpha-blockers, blood-pressure medicines and medicines such as ritonavir, ketoconazole or erythromycin. If it doesn't work as you expect, see a doctor — hormonal or circulation problems are worth ruling out, as our avanafil guide explains.
Kam4eu supplies Avana 50 as a factory-sealed product with the batch number and expiry visible on the blister and the patient leaflet enclosed, so you can check what you receive. Orders are dispatched within one working day of payment in plain packaging with no pharmacy branding, with tracking on every parcel; standard delivery takes 3–5 working days to most EU and EEA countries (2–7 by country) and is free over €110. Packs start at €20.00 for 1 Strip / 4 pills.
Avana 50 shares the side-effect list of every avanafil tablet: common reactions listed in the leaflet can occur: headache, facial flushing, a blocked or stuffy nose, back pain and mild dizziness. These are usually mild and pass within hours. Rare but serious effects still apply at 50 mg: a painful erection lasting over four hours (priapism), sudden vision loss or dimming, sudden hearing loss or tinnitus, and chest pain during sexual activity. Any of these means stop the medicine and seek medical help straight away. If side effects trouble you, tell your doctor.
Even at this low strength, the absolute rule stands: never combine Avana 50 with nitrates (angina medicines like glyceryl trinitrate or isosorbide) or with poppers (amyl or butyl nitrite). Together they can drop blood pressure to dangerous levels. Use caution with alpha-blockers such as tamsulosin or doxazosin — timing and dose separation matter. Men with severe heart failure, unstable angina, a recent heart attack or stroke, very low or uncontrolled blood pressure, or significant liver or kidney disease need a doctor's clearance first. Avoid avanafil if sex itself has been judged unsafe for your heart, if you take strong CYP3A4 inhibitors like ritonavir or ketoconazole, or if you have previously reacted to avanafil.
Store Avana 50 below 25–30 °C in a cool, dry spot, keeping tablets in their original sealed blister until the moment you take one. Avoid bathrooms and windowsills where heat and moisture degrade tablets, and keep the pack well out of children's reach. Authenticity checks take thirty seconds: the blister foil should be uniformly sealed with no punctures, the batch number and expiry date must be printed on both the blister strip and the outer box and should match, the box should contain a patient information leaflet, and the carton should arrive undamaged. Anything missing or tampered with — don't take it; contact us instead.
Current prices: 1 Strip / 4 pills for €20.00 (€5.00 per pill), 5 Strip / 20 pills for €90.00 (€4.50 per pill) and 10 Strip / 40 pills for €150.00 (€3.75 per pill). Buying 10 Strip / 40 pills works out 25% cheaper per pill than the smallest pack. Buy only what you will use before the printed expiry date.
General information about the active ingredient in Avana 50.
See the full Avanafil guide & all Avanafil productsAvanafil is a prescription-only medicine in the EU/EEA used to treat erectile dysfunction in adult men. It belongs to the class of medicines known as phosphodiesterase type 5 (PDE5) inhibitors and is the active substance of Spedra, the avanafil medicine authorised across the EU through the European Medicines Agency. Sexual stimulation is needed for it to work.
Avanafil is a highly selective, reversible inhibitor of the PDE5 enzyme. When sexual stimulation releases nitric oxide in the penis, blocking PDE5 lets cyclic guanosine monophosphate (cGMP) build up, which relaxes the smooth muscle and lets blood flow into the penile tissue to produce an erection. The EU product information states that avanafil has no effect without sexual stimulation. It is absorbed quickly: peak blood levels are reached roughly 30 to 45 minutes after a dose taken on an empty stomach.
Avanafil is taken by mouth, as needed, approximately 15 to 30 minutes before sexual activity, at the dose your doctor prescribes. It must not be taken more than once a day. It can be taken with or without food, but the EU product information notes that taking it with food may delay the start of its effect. Your doctor may use a lower dose if you take certain other medicines or have mild to moderate liver problems. Always follow the patient information leaflet.
Common (usually mild and temporary):
Stop and seek medical help if you experience:
Store in the original packaging out of the sight and reach of children, and do not use after the expiry date. The EU product information states no special storage conditions are required.
The EU product information for Spedra says to take it approximately 15 to 30 minutes before sexual activity. In a clinical study some men had an erection sufficient for penetration as early as 20 minutes after a dose. Sexual stimulation is still needed, and response varies between men.
The EU product information gives no fixed duration window for avanafil, unlike tadalafil's. It reports a terminal half-life of roughly 6 to 17 hours, which describes how the drug leaves the body rather than how long an erection response lasts. Do not take more than one dose a day.
It can be taken with or without food, though food may delay the start of its effect. The EU product information advises against combining it with alcohol, because the two together increase the chance of low blood pressure, dizziness and fainting.
Nitrates for angina, nitric-oxide donors such as amyl nitrite ('poppers'), riociguat, and potent CYP3A4 inhibitors such as ketoconazole, itraconazole, ritonavir and clarithromycin. Tell your doctor about every medicine you take, including alpha-blockers and other blood-pressure medicines.
All three are PDE5 inhibitors. According to their EU product information, avanafil is taken about 15 to 30 minutes before sex, sildenafil about 1 hour before, and tadalafil at least 30 minutes before, with tadalafil showing a response up to 36 hours after the dose. The comparison table on this page lists the details.
Avanafil is the active substance in Spedra. A generic product contains the same active substance, but only medicines with an EU or national marketing authorisation have been assessed by a European regulator. Avanafil is prescription-only in the EU/EEA.
Important: This information is general and not a substitute for medical advice. Always read the patient information leaflet supplied with your medicine and consult a doctor or pharmacist before use — especially if you have existing health conditions or take other medication.
The larger the pack, the lower the price per unit.
Avana options that contain avanafil alone, with their current list prices. A higher strength is not better value: the EU product information has a doctor set the dose by how the medicine works for you and how well you tolerate it.
Avana 50 isn't stocked on European high-street pharmacy shelves — it's an imported generic, so buying happens online. Kam4eu ships sealed Avana 50 from €20.00 (3 pack sizes, lower per-unit price on larger packs) to all 27 EU + 3 EEA countries. Orders dispatch within one working day of payment; standard delivery takes 3–5 working days to most EU/EEA countries (2–7 by country), free over €110.00. Unsure about the legal side? Our honest legality answers explains the brand-vs-ingredient distinction plainly.
Avana 50 starts from €20.00. Several pack sizes are available — the larger the pack, the lower the per-unit price. European delivery is free on orders over €110, otherwise €20 standard (3–5 working days to most countries, 2–7 by country).
Orders ship in plain, unbranded packaging from our European fulfilment hub, usually within one working day of payment clearing. Standard delivery reaches all 27 EU + 3 EEA countries in 3–5 working days to most of them (2–7 depending on the country); express (1–2 working days) is also available. For EU orders, VAT and duties are settled at checkout via IOSS, so there are no surprise bills on arrival.
The active ingredient in Avana 50 is Avanafil. Always read the patient information leaflet and consult a doctor or pharmacist before first use.
Choose your method at checkout: secure bank/SEPA transfer or PayPal. You'll receive clear payment confirmation by email, and we dispatch within one working day of payment clearing.
Yes. Every order ships in plain, unbranded outer packaging — nothing on the outside indicates the contents or the pharmacy.
50 mg is one of the doses in the EU product information for Spedra, which recommends 100 mg and lets a doctor lower it to 50 mg or raise it to 200 mg; men already taking alpha-blockers should initially be given 50 mg. How a dose works differs between men, so whether 50 mg suits you is your doctor's decision.
That is your doctor's decision. The Spedra product information recommends 100 mg for most men and names 50 mg for some, such as men taking alpha-blockers. Speak to a doctor before starting any ED medicine, particularly if you have heart problems, take nitrates, or have other significant health conditions.
The EU product information for Spedra says avanafil is taken about 15 to 30 minutes before sexual activity, at any strength (EMA: Spedra), and that food may delay its effect. The tablet only works together with sexual arousal — it does not cause erections on its own.
No. Never change your dose by combining tablets — the maximum is one dose in any 24-hour period, and any change of dose is your doctor's decision.
Current prices: 1 Strip / 4 pills for €20.00 (€5.00 per pill), 5 Strip / 20 pills for €90.00 (€4.50 per pill) and 10 Strip / 40 pills for €150.00 (€3.75 per pill). Buying 10 Strip / 40 pills works out 25% cheaper per pill than the smallest pack. Orders are dispatched within one working day of payment in plain packaging with no pharmacy branding, with tracking on every parcel; standard delivery takes 3–5 working days to most EU and EEA countries (2–7 by country) and is free over €110.
The Spedra product information says avanafil can be taken with or without food, but that taking it with food may delay the start of its effect. Grapefruit juice is best avoided, as it can raise avanafil levels. Your doctor and the package leaflet set how it applies to you.
Don't take another tablet within 24 hours. Nerves, food, alcohol and a lack of arousal can all affect how avanafil works, as the package leaflet explains. If it doesn't work as you expect, talk to your doctor rather than changing the dose yourself.
The EU product information gives avanafil's timing but no fixed duration of effect. Whatever the effect, wait a full 24 hours before any next dose.
Avanafil is a prescription-only medicine across the EU/EEA, Avana has no EU marketing authorisation, and rules on personal importation vary by country. Speak to a doctor and get a valid prescription first, and check your national regulations.
Yes. Every blister and box carries a printed expiry date. Do not take tablets past that date, and keep them cool, dry and sealed in the original blister until then.
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Reviewed by the Kam4eu editorial teamMedicine information reviewed 13 August 2026Next review due 13 August 2027
Sources for the medical information on this page
This page is general product and medicine information, not a prescription or a substitute for medical advice. Always read the patient information leaflet supplied with your medicine, and speak to a doctor or pharmacist before starting Avana 50 — especially if you take other medicines or have a heart, liver or kidney condition.